The Spanish actress, who has a 23-month-old daughter, India, with husband Chris Hemsworth, gave birth to twin boys, Sasha and Tristan, in late March, and admits she is still adjusting to their new additions.
The 37-year-old star wrote in a Q&A with fans on her blog for Spain's Glamour magazine: "(We) do not plan to have more children, but you can never say never."
She added: "With twins you have more work, and now I have to do it better."
She also dismissed speculation that Chris' pal, Tom Hiddleston, is their daughter's godfather.
Elsa, who will appear in 'Fast & Furious 7,' currently has no other acting projects lined up, as she wants to stay at home with her family.
She said: "My children right now is what matters most to me."
The blonde beauty lives in Los Angeles with 'Thor' star Chris, 30, and initially found it difficult to settle into the city after moving over from her native Madrid.
She said: "At first Los Angeles was a tough town for me because the lifestyle is very different from ours. But I've always thought that if you want to achieve something or pursue your dreams you have to make sacrifices. It all depends on what is most important to you."
She added: "I think I'm always being a positive person, even in the worst moments I try to see the bright side.